The episode starts 10 months after the events in "Original Sin" and circumstances have changed for the main characters (for some more than for others). Two of them are pretty different from the last time we saw them, and the team might be missing a member or two. Or more.
The title on the production draft dated 21/02 is "Wake-up Call."
Returning guest characters: Stanton Parish, Danielle Rosen, Nathan Clay
The character they were casting last month? Not so sure she'll be introduced in this episode.
Some of the characters being cast in 2x01:
Meg, Dumpy, Unassuming Man (a group of criminals with special abilities)
Warden (of Binghamton)
William the Guard (a prison guard)
Scipio, Kimi, Asher (some of Binghamton's greatest hits)
Hulking Psychopath (a prisoner)
Yeah, a good chunk of the episode is set at Binghamton. And any worries that the show is being turned into Eureka in tone this season should be out the window in the first 15 minutes or so.